Doxa, founded in 1889 by Georges Ducommun, began as a maker of dress watches and other timepieces. Over the years, Doxa gained in size and branched out into other timekeeping markets. (Wristwatches, Armbanduhren, Montres-bracelets; Brunner, Gisbert L; Pfeiffer-Belli, Christian; Koneman, 2006)

In the late 1960s Doxa decided to devote resources to create a watch to be used for diving. Tests indicated that an orange face was more visible in murky water. Doxa also consulted with divers, including Jacques Cousteau, then chairman of "U.S. Divers," and Claude Wesly (a Cousteau companion and the first man to spend seven days thirty-three feet underwater). A staff of engineers and professional divers was assembled to create a watch with the required features. The Sub300t was purchased in quantity by U.S. Divers, who resold the watch in the United States.

The Jenny family of Switzerland now owns the brand. Since August 2002, Doxa has introduced re-editions of its watches and timepieces in limited quantities. Many are reproductions of the original models in design and construction, and all use Swiss movements.